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Aggressive periodontitis describes a type of periodontal disease and includes two of the seven classifications of periodontitis: # Localized aggressive periodontitis (LAP) # Generalized aggressive periodontitis (GAP) Aggressive periodontitis is much less common than chronic periodontitis and generally affects younger patients than does the chronic form. The localized and generalized forms are not merely different in extent; they differ in etiology and pathogenesis. ==Characteristics== In contrast to chronic periodontitis, primary features that are common to both LAP and GAP are as follows: * except for the presence of periodontal disease, patients are otherwise healthy * rapid loss of attachment and bone destruction * familial aggregation * Depressed neutrophil function. * Neutrophils (PMN's) are defective, resulting in depressed chemotaxis and phogocytosis. The first feature mentioned is to say that patients may not exhibit any disorder that predisposes one to another form of periodontitis. Moreover, aggressive periodontitis often presents with the following secondary features:〔 * Amounts of microbial deposits are inconsistent with the severity of the periodontal tissue destruction * elevated proportions of ''Aggregatibacter actinomycetemcomitans'', and in some cases, of ''Porphyromonas gingivalis'' as well * phagocyte abnormalities * hyperresponsive macrophage phenotype, including elevated levels of prostaglandin E2 (PGE2) and interleukin 1β * progression of pathogenesis may be self-limiting 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Aggressive periodontitis」の詳細全文を読む スポンサード リンク
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